Issue 78, 2014
From the journal:

Chemical Communications

A facilely synthesized amino-functionalized metal–organic framework for highly specific and efficient enrichment of glycopeptides†

Yi-Wei Zhang,a   Ze Li,a   Qiang Zhao,a   Ying-Lin Zhou,a   Hu-Wei Liua  and  Xin-Xiang Zhang*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry, Peking University, Beijing 100871, China
E-mail: zxx@pku.edu.cn
Fax: +86-10-62754112
Tel: +86-10-62754112

Abstract

A facilely synthesized amino-functionalized metal–organic framework (MOF) MIL-101(Cr)-NH2 was first applied for highly specific glycopeptide enrichment based on the hydrophilic interactions. With the special characteristics of the MOF, the material performed well in selectivity and sensitivity for both standard glycoprotein samples and complex biological samples.

Graphical abstract: A facilely synthesized amino-functionalized metal–organic framework for highly specific and efficient enrichment of glycopeptides

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Article information

DOI
https://doi.org/10.1039/C4CC05179C
Article type
Communication
Submitted
05 Jul 2014
Accepted
05 Aug 2014
First published
05 Aug 2014

Chem. Commun., 2014,50, 11504-11506

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A facilely synthesized amino-functionalized metal–organic framework for highly specific and efficient enrichment of glycopeptides

Y. Zhang, Z. Li, Q. Zhao, Y. Zhou, H. Liu and X. Zhang, Chem. Commun., 2014, 50, 11504 DOI: 10.1039/C4CC05179C

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