Issue 86, 2014
From the journal:

Chemical Communications

One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin†

Cheng Zheng,a   Ai-Xian Zheng,a   Bo Liu,a   Xiao-Long Zhang,a   Yu He,*a   Juan Li,a   Huang-Hao Yang*a  and  Guonan Chena  

* Corresponding authors

a The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350002, People's Republic of China
E-mail: hhyang@fio.org.cn, heyu@fzu.edu.cn

Abstract

We developed a facile one-step approach to synthesize DNA-templated Ag/Pt bimetallic nanoclusters (DNA–Ag/Pt NCs), which possess highly-efficient peroxidase-like catalytic activity. With this finding, an aptamer based sandwich-type strategy is employed to design a label-free colorimetric aptasensor for the protein detection with high sensitivity and selectivity.

Graphical abstract: One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin

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Article information

DOI
https://doi.org/10.1039/C4CC05339G
Article type
Communication
Submitted
11 Jul 2014
Accepted
02 Sep 2014
First published
03 Sep 2014

Chem. Commun., 2014,50, 13103-13106

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One-pot synthesized DNA-templated Ag/Pt bimetallic nanoclusters as peroxidase mimics for colorimetric detection of thrombin

C. Zheng, A. Zheng, B. Liu, X. Zhang, Y. He, J. Li, H. Yang and G. Chen, Chem. Commun., 2014, 50, 13103 DOI: 10.1039/C4CC05339G

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