Issue 55, 2015
From the journal:

Chemical Communications

Room temperature freezing and orientational control of surface-immobilized peptides in air†

Yaoxin Li,a   Xiaoxian Zhang,a   John Myers,a   Nicholas L. Abbottb  and  Zhan Chen*a  

* Corresponding authors

a Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA
E-mail: zhanc@umich.edu

b Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA

Abstract

Sugar coatings can stabilize the “native” structure and control the orientation of surface-immobilized peptides in air, providing a potential approach to retain biological functions of surface-immobilized biomolecules in air. This method is general and applicable to complex enzymes.

Graphical abstract: Room temperature freezing and orientational control of surface-immobilized peptides in air

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Article information

DOI
https://doi.org/10.1039/C5CC03274A
Article type
Communication
Submitted
20 Apr 2015
Accepted
29 May 2015
First published
04 Jun 2015

Chem. Commun., 2015,51, 11015-11018

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Room temperature freezing and orientational control of surface-immobilized peptides in air

Y. Li, X. Zhang, J. Myers, N. L. Abbott and Z. Chen, Chem. Commun., 2015, 51, 11015 DOI: 10.1039/C5CC03274A

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