Synthesis of a cyclometalated 1,3,5-triphenylpyrazole palladium dimer and its activity towards cross coupling reactions

Abstract

A phosphine free 1,3,5-triphenylpyrazole acetate-bridged palladacycle was prepared from simple commercially available starting materials. The activity of the palladacycle in the Mizoroki–Heck and Suzuki–Miyaura cross-coupling reactions was evaluated. The palladacycle precatalyst shows a wide substrate scope, both in Mizoroki–Heck as well as in Suzuki–Miyaura cross-coupling reactions using low catalyst loadings viz., 0.2 mol% and 0.1 mol% respectively.