Issue 4, 2015

A chiral borane catalyzed asymmetric hydrosilylation of imines

Abstract

An enantioselective hydrosilylation of imines was successfully achieved using a chiral borane catalyst generated by the in situ hydroboration of a binaphthyl-based chiral diene with Piers’ borane HB(C6F5)2 to furnish a variety of optically active amines in 70% to >99% yields and 44–82% ees.

Graphical abstract: A chiral borane catalyzed asymmetric hydrosilylation of imines

Supplementary files

Article information

Article type
Communication
Submitted
18 Nov 2014
Accepted
28 Nov 2014
First published
28 Nov 2014

Org. Biomol. Chem., 2015,13, 1013-1016

A chiral borane catalyzed asymmetric hydrosilylation of imines

X. Zhu and H. Du, Org. Biomol. Chem., 2015, 13, 1013 DOI: 10.1039/C4OB02419B

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