A simple palladium-catalysed oxidative cross-coupling between two different alcohols was developed. Various benzylic alcohols could couple with aliphatic alcohols in excellent yields. The use of benzyl chloride as the oxidant and the amount of aliphatic alcohol were both important for achieving the reaction selectivity.
J. Xia, A. Shao, S. Tang, X. Gao, M. Gao and A. Lei, Org. Biomol. Chem., 2015, 13, 6154 DOI: 10.1039/C5OB00677E
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