Direct manipulation of particle size and morphology of ordered mesoporous silica by flow synthesis

Abstract

The precision by which the fluid mixing, flow pattern, and reaction can be manipulated in a flow-synthesis reactor enables the deliberate preparation of ordered mesoporous silicas (OMS) of controlled particle size (ca. 50 to 650 nm) and shapes (i.e., spheres and random), as well as complex microstructures (i.e., hollow spheres). Fluid mixing and flow pattern were generated using Tee- and slit interdigital micromixers under laminar and Taylor flow conditions, while hydrolysis reactions was governed by the alkoxide precursors (i.e. TEOS & TMOS) and temperature. The hollow OMS spheres can host molecules and clusters as demonstrated by the incorporation of ferrocene and iron nanoparticles.