Issue 6, 2016

A novel biocompatible europium ligand for sensitive time-gated immunodetection

Abstract

We describe the synthesis of a novel hydrophilic derivative of a tetradentate β-diketone europium ligand that was used to prepare an immunoconjugate probe against Giardia lamblia cysts. We used a Gated Autosynchronous Luminescence Detector (GALD) to obtain high quality delayed luminescence images of cells 30-fold faster than ever previously reported.

Graphical abstract: A novel biocompatible europium ligand for sensitive time-gated immunodetection

Supplementary files

Article information

Article type
Communication
Submitted
13 Aug 2015
Accepted
20 Nov 2015
First published
20 Nov 2015

Chem. Commun., 2016,52, 1154-1157

Author version available

A novel biocompatible europium ligand for sensitive time-gated immunodetection

N. Sayyadi, R. E. Connally and A. Try, Chem. Commun., 2016, 52, 1154 DOI: 10.1039/C5CC06811H

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