Issue 62, 2016

Research progress in electroanalytical techniques for determination of antimalarial drugs in pharmaceutical and biological samples

Abstract

Antimalarial drugs play a crucial role in the treatment and cure of malaria. Electrochemical sensors have been the subject of extensive research in the field of drug analysis since many decades, and yet seem to project great potential for the future. The present review explores the basic strategies and recent developments in the electroanalysis of antimalarial drugs in various matrices. A discussion of the commonly used electroanalytical methods for drug assays is briefly discussed. The methods have been critically analysed highlighting their analytical performance and limitations. Nanomaterials, conducting polymers and presence of surfactants made significant contributions to voltammetric determination of antimalarial drugs suggesting promising future for use of chemically-modified electrode based sensors for the detection. Future progress in quantification of these drugs in biological fluids is expected to drastically improve the applicability of electrochemical methods for routine clinical analysis.

Graphical abstract: Research progress in electroanalytical techniques for determination of antimalarial drugs in pharmaceutical and biological samples

Article information

Article type
Review Article
Submitted
25 Feb 2016
Accepted
01 Jun 2016
First published
10 Jun 2016

RSC Adv., 2016,6, 57580-57602

Research progress in electroanalytical techniques for determination of antimalarial drugs in pharmaceutical and biological samples

N. Thapliyal, T. E. Chiwunze, R. Karpoormath, R. N. Goyal, H. Patel and S. Cherukupalli, RSC Adv., 2016, 6, 57580 DOI: 10.1039/C6RA05025E

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