Issue 10, 2017

Regioselective switching approach for the synthesis of α and δ carboline derivatives

Abstract

A metal-free protocol for accessing both α and δ-carboline derivatives, starting from a common indolylchalcone oxime ester precursor is reported. The reaction involves mild conditions and uses a regiodivergent approach. DDQ is used as a switching agent in selectively generating α and δ-carboline derivatives in good to moderate yields.

Graphical abstract: Regioselective switching approach for the synthesis of α and δ carboline derivatives

Supplementary files

Article information

Article type
Communication
Submitted
29 Nov 2016
Accepted
10 Jan 2017
First published
10 Jan 2017

Chem. Commun., 2017,53, 1676-1679

Regioselective switching approach for the synthesis of α and δ carboline derivatives

T. Yang, C. Kuo, V. Kavala, A. Konala, C. Huang and C. Yao, Chem. Commun., 2017, 53, 1676 DOI: 10.1039/C6CC09468F

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