Issue 29, 2018
From the journal:

Chemical Communications

Folate decorated hollow spheres of microporous organic networks as drug delivery materials†

June Young Jang,‡a   Huu Thuy Trang Duong,‡b   Sang Moon Lee,c   Hae Jin Kim,c   Yoon-Joo Ko,d   Ji Hoon Jeong,e   Doo Sung Lee, ORCID logo *b   Thavasyappan Thambi ORCID logo *b  and  Seung Uk Son ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Sungkyunkwan University, Suwon 16419, Korea
E-mail: sson@skku.edu

b School of Chemical Engineering, Theranostic Macromolecules Research Center, Sungkyunkwan University, Suwon 16419, Korea
E-mail: dslee@skku.edu, thambi@skku.edu

c Korea Basic Science Institute, Daejeon 34133, Korea

d Laboratory of Nuclear Magnetic Resonance, The National Center for Inter-University Research Facilities (NCIRF), Seoul National University, Seoul 08826, Korea

e School of Pharmacy, Theranostic Macromolecules Research Center, Sungkyunkwan University, Suwon 16419, Korea

Abstract

Hollow and microporous organic network spheres decorated with folic acids (H-MON-FA) were prepared using silica templates by the Sonogashira coupling of organic building blocks and successive post-synthetic modifications. The drug (DOX) delivery performance of H-MON-FA to cancer cells was studied.

Graphical abstract: Folate decorated hollow spheres of microporous organic networks as drug delivery materials

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Article information

DOI
https://doi.org/10.1039/C8CC01240G
Article type
Communication
Submitted
12 Feb 2018
Accepted
18 Mar 2018
First published
19 Mar 2018

Chem. Commun., 2018,54, 3652-3655

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Folate decorated hollow spheres of microporous organic networks as drug delivery materials

J. Y. Jang, H. T. T. Duong, S. M. Lee, H. J. Kim, Y. Ko, J. H. Jeong, D. S. Lee, T. Thambi and S. U. Son, Chem. Commun., 2018, 54, 3652 DOI: 10.1039/C8CC01240G

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