N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines

Weiguang Yang; Dayun Huang; Xiaobao Zeng; Dongping Luo; Xinyan Wang; Yuefei Hu

doi:10.1039/C8CC04699A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines†

Weiguang Yang,^a Dayun Huang,^a Xiaobao Zeng,^a Dongping Luo,^a Xinyan Wang*^a and Yuefei Hu

*^a

Author affiliations

* Corresponding authors

^a Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China
E-mail: wangxinyan@mail.tsinghua.edu.cn, yfh@mail.tsinghua.edu.cn

Abstract

A highly reactive intermediate N-sulfonyl acetylketenimine was generated from a 3-butyn-2-one participating CuAAC/ring-opening method. Its high reactivity due to bearing two EWGs allowed us to offer the first example of a reaction between ketenimine and amide to synthesize N-sulfonyl amidines efficiently.

Download options Please wait...

Supplementary files

Supplementary information PDF (3416K)

Article information

DOI: https://doi.org/10.1039/C8CC04699A
Article type: Communication
Submitted: 12 Jun 2018
Accepted: 03 Jul 2018
First published: 03 Jul 2018

Download Citation

Chem. Commun., 2018,54, 8222-8225

Permissions

Request permissions

N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines

W. Yang, D. Huang, X. Zeng, D. Luo, X. Wang and Y. Hu, Chem. Commun., 2018, 54, 8222 DOI: 10.1039/C8CC04699A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines†

Abstract

Supplementary files

Article information

Download Citation

Permissions

N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines

Social activity

Search articles by author

Spotlight

Advertisements