Issue 25, 2018
From the journal:

Nanoscale

Fluorous interaction induced self-assembly of tobacco mosaic virus coat protein for cisplatin delivery†

Sijia Gao,ab   Xiangxiang Liu,ac   Zhaocheng Wang,a   Shidong Jiang, ORCID logo a   Man Wu, ORCID logo a   Ye Tian ORCID logo *a  and  Zhongwei Niu ORCID logo *ad  

* Corresponding authors

a Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: niu@mail.ipc.ac.cn, tiany@mail.ipc.ac.cn

b University of Chinese Academy of Sciences, Beijing 100049, China

c School of Chemistry and Chemical Engineering, Beijing Institute of Technology, No. 5, Zhongguancun South Street, Beijing 100081, China

d School of Future Technology, University of Chinese Academy of Sciences, Beijing 100049, China

Abstract

Tobacco mosaic virus coat protein was modified with a small molecular fluorous ponytail at specific sites, and self-assembled into spherical nanoparticles through fluorous interaction induced self-assembly. By loading the anti-cancer drug cisplatin through metal–ligand coordination, this spherical assembly with high stability has potential as a drug carrier.

Graphical abstract: Fluorous interaction induced self-assembly of tobacco mosaic virus coat protein for cisplatin delivery

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Article information

DOI
https://doi.org/10.1039/C8NR03748E
Article type
Communication
Submitted
09 May 2018
Accepted
31 May 2018
First published
01 Jun 2018

Nanoscale, 2018,10, 11732-11736

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Fluorous interaction induced self-assembly of tobacco mosaic virus coat protein for cisplatin delivery

S. Gao, X. Liu, Z. Wang, S. Jiang, M. Wu, Y. Tian and Z. Niu, Nanoscale, 2018, 10, 11732 DOI: 10.1039/C8NR03748E

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