We report a concise, versatile, and practical method for PhI(OCOCF3)2 mediated direct meta-C–H monohalogenation of 2-phenylpyridine and its derivatives via an Ru(I)-catalyzed reaction. The significant advantage of this transformation is the creation of a highly site-selective C–X bond by using NXS as halogenating agents under mild reaction conditions.
G. M. Reddy, N. S. Rao and H. Maheswaran, Org. Chem. Front., 2018, 5, 1118 DOI: 10.1039/C7QO01133D
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