Issue 11, 2018, Issue in Progress

A feasible strategy for self-assembly of gold nanoparticles via dithiol-PEG for photothermal therapy of cancers

Abstract

We designed and explored self-assembled gold nanoparticles (SAGNPs) by introducing dithiol modified polyethylene glycol (PEG) for internanoparticle cross-linking. SAGNPs could enhance uptake into cancer cells and be disintegrated by glutathione (GSH) to achieve tumor microenvironment-activated biodegradation. This assembled structure improved the photothermal effect compared to single gold nanospheres.

Graphical abstract: A feasible strategy for self-assembly of gold nanoparticles via dithiol-PEG for photothermal therapy of cancers

Supplementary files

Article information

Article type
Paper
Submitted
24 Nov 2017
Accepted
31 Jan 2018
First published
07 Feb 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 6120-6124

A feasible strategy for self-assembly of gold nanoparticles via dithiol-PEG for photothermal therapy of cancers

Y. Fu, Q. Feng, Y. Shen, M. Chen, C. Xu, Y. Cheng and X. Zhou, RSC Adv., 2018, 8, 6120 DOI: 10.1039/C7RA12735A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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