A novel strategy for the regiospecific synthesis of 2-(2-aminobenzoyl)benzoic acids via a base-promoted aerobic cascade reaction has been exploited. The protocol led to a wide panel of 2-(2-aminobenzoyl)benzoic acids with a broad substrate scope in an atom-economical manner. Six new bonds were sequentially formed in this one-pot procedure.
J. Shen, Y. Chen, T. Chen, Z. Zou, Y. Feng and Q. You, Org. Chem. Front., 2019, 6, 1383 DOI: 10.1039/C9QO00101H
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