The first examples of 1,7-orthogonally diprotected cyclen (1,4,7,10-tetraazacyclododecane) derivatives have been prepared through a straightforward and convenient synthetic strategy. These compounds represent useful starting materials for the preparation of several functionalised macrocyclic chelating agents.
F. Travagin, L. Lattuada and G. B. Giovenzana, Org. Chem. Front., 2019, 6, 1387 DOI: 10.1039/C9QO00184K
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