Issue 50, 2020
From the journal:

Chemical Communications

Nickel-catalyzed hydrogen-borrowing strategy: chemo-selective alkylation of nitriles with alcohols†

Sourajit Bera,a   Atanu Beraa  and  Debasis Banerjee ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Laboratory of Catalysis and Organic Synthesis, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India
E-mail: debasis.banerjee@cy.iitr.ac.in

Abstract

The first nickel-catalyzed hydrogen-borrowing alkylation of a series of aryl acetonitriles with a variety of aryl, heteroaryl, allylic and alkyl alcohols releasing water as the by-product (>33 examples, up to 90% yield) is reported.

Graphical abstract: Nickel-catalyzed hydrogen-borrowing strategy: chemo-selective alkylation of nitriles with alcohols

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Article information

DOI
https://doi.org/10.1039/D0CC02261F
Article type
Communication
Submitted
27 Mar 2020
Accepted
24 Apr 2020
First published
24 Apr 2020

Chem. Commun., 2020,56, 6850-6853

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Nickel-catalyzed hydrogen-borrowing strategy: chemo-selective alkylation of nitriles with alcohols

S. Bera, A. Bera and D. Banerjee, Chem. Commun., 2020, 56, 6850 DOI: 10.1039/D0CC02261F

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