Issue 14, 2021
From the journal:

Analyst

Universal colorful staining of cancer tissues and normal tissues for histological diagnosis†

Jin-Mei Lia  and  Ke-Rang Wang ORCID logo *bc  

* Corresponding authors

a Department of Pathology, The First Central Hospital of Baoding, Baoding, China

b College of chemistry and environmental science, Hebei University, Baoding, P. R. China
E-mail: kerangwang@hbu.edu.cn

c Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Key Laboratory of Chemical Biology of Hebei Province, Hebei University, Baoding, P. R. China

Abstract

The versatility of multicolor imaging of human tissues based on staining with perylene monoimide–mannose conjugates PMI-Man and co-staining with PMI-Man and eosin (P&E) was investigated for human cancer and normal tissues. Staining with PMI-Man or co-staining with PMI-Man and eosin showed a perfect histological morphology both in confocal fluorescence microscopy and light microscopy. This approach provided a universal colorful staining method for cancer tissues and normal tissues.

Graphical abstract: Universal colorful staining of cancer tissues and normal tissues for histological diagnosis

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Article information

DOI
https://doi.org/10.1039/D1AN00570G
Article type
Communication
Submitted
05 Apr 2021
Accepted
31 May 2021
First published
01 Jun 2021

Analyst, 2021,146, 4446-4449

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Universal colorful staining of cancer tissues and normal tissues for histological diagnosis

J. Li and K. Wang, Analyst, 2021, 146, 4446 DOI: 10.1039/D1AN00570G

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