Issue 42, 2023
From the journal:

Chemical Communications

Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy†

Zi-Chun Chia, ORCID logo a   Yi-Lun Chen,b   Cheng-Hsun Chuang,b   Chou-Hsun Hsieh,b   Ya-Jyun Chen,a   Kuan-Hsu Chen,a   Tzu-Chi Huang, ORCID logo a   Mei-Chin Chen ORCID logo *b  and  Chih-Chia Huang ORCID logo *ac  

* Corresponding authors

a Department of Photonics, National Cheng Kung University, Tainan 70101, Taiwan

b Department of Chemical Engineering, National Cheng Kung University, Tainan 70101, Taiwan
E-mail: kokola@mail.ncku.edu.tw

c Center of Applied Nanomedicine, National Cheng Kung University, Tainan 70101, Taiwan
E-mail: c2huang@mail.ncku.edu.tw

Abstract

3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 102 CFU cm−2 for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.

Graphical abstract: Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/D3CC00733B
Article type
Communication
Submitted
16 Feb 2023
Accepted
19 Apr 2023
First published
20 Apr 2023

Chem. Commun., 2023,59, 6339-6342

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Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

Z. Chia, Y. Chen, C. Chuang, C. Hsieh, Y. Chen, K. Chen, T. Huang, M. Chen and C. Huang, Chem. Commun., 2023, 59, 6339 DOI: 10.1039/D3CC00733B

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