Issue 3, 2024

C–H borylation: a tool for molecular diversification

Abstract

Iridium-catalyzed C–H activation and borylation has become as a powerful synthetic tool in the past few decades because of the widespread applicability and versatility of organoboron compounds. This reaction is currently receiving extensive research interest in both academia and pharmaceutical industries because of its ability to attain a high degree of molecular complexity from simple building blocks. This review aims to highlight the implementation of C–H activation and borylation strategies in tandem one-pot transformations for the synthesis of complex natural products, for the late-stage modifications of bio-active molecules and pharmaceuticals, and for the functionalization of aromatic polycyclic systems used in materials chemistry.

Graphical abstract: C–H borylation: a tool for molecular diversification

Article information

Article type
Review Article
Submitted
22 Nov 2023
Accepted
18 Dec 2023
First published
19 Dec 2023

Org. Chem. Front., 2024,11, 929-953

C–H borylation: a tool for molecular diversification

S. Guria, M. M. M. Hassan and B. Chattopadhyay, Org. Chem. Front., 2024, 11, 929 DOI: 10.1039/D3QO01931D

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