Issue 49, 2024

Iron-catalyzed aerobic oxidation of silyl ethers to carboxylic acids

Abstract

Direct aerobic oxidation of silyl ethers to carboxylic acids has been developed. The mild reaction conditions lead to a broad range of functional group compatibility. Different types of silyl groups have been investigated and selective deprotective oxidation has been realized. The reaction could be conducted under air.

Graphical abstract: Iron-catalyzed aerobic oxidation of silyl ethers to carboxylic acids

Supplementary files

Article information

Article type
Communication
Submitted
18 Mar 2024
Accepted
22 Apr 2024
First published
23 Apr 2024

Chem. Commun., 2024,60, 6272-6275

Iron-catalyzed aerobic oxidation of silyl ethers to carboxylic acids

Z. Lin and S. Ma, Chem. Commun., 2024, 60, 6272 DOI: 10.1039/D4CC01234H

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