ipso-Attack in the hydroxylation of o- and p-xylene using bis(trimethylsilyl) peroxide and aluminium chloride
Abstract
Electrophilic hydroxylation of o- and p-xylene using a range of peroxides, including the title compound, in the presence of Lewis acids results in the formation of mixtures of phenols including those derived by ipso-attack followed by rearrangement; ipso-attack by the hydroxyl radical leads to dealkylation.