Regioselective alkylation of 1(3)-acetyl-4H,6H-thieno[3,4-c]furan 5,5-dioxide
Abstract
Reaction of the title compound 2 with a variety of alkylating agents regioselectively gave, depending on the reaction conditions used, 4-alkylated compound 3 or 6-alkylated compound 4, which were further alkylated to afford the dialkylated compounds 5–7 in similar ways.