Issue 6, 2002
From the journal:

Chemical Communications

Direct catalytic asymmetric aldol reactions of aldehydes

Anders Bøgevig,a   Nagaswamy Kumaragurubarana  and  Karl Anker Jørgensen*a  

* Corresponding authors

a Center for Metal Catalyzed Reactions, Department of Chemistry, Aarhus University, DK-8000, Aarhus C, Denmark
E-mail: kaj@chem.au.dk
Fax: 45-8619-6199
Tel: 45-8942 3910

Abstract

The development of a direct catalytic enantioselective aldol reaction of aldehydes with activated carbonyl compounds catalyzed by chiral amines is presented and the potential demonstrated by the synthesis of optically active β-hydroxycarboxylic acid derivatives.

Graphical abstract: Direct catalytic asymmetric aldol reactions of aldehydes

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Article information

DOI
https://doi.org/10.1039/B200681B
Article type
Communication
Submitted
22 Jan 2002
Accepted
08 Feb 2002
First published
22 Feb 2002

Chem. Commun., 2002, 620-621

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Direct catalytic asymmetric aldol reactions of aldehydes

A. Bøgevig, N. Kumaragurubaran and K. Anker Jørgensen, Chem. Commun., 2002, 620 DOI: 10.1039/B200681B

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