Issue 13, 2010
From the journal:

Chemical Communications

A totally synthetic glucose responsive gel operating in physiological aqueous conditions†

Akira Matsumoto,a   Kazuya Yamamoto,b   Ryo Yoshida,a   Kazunori Kataoka,a   Takao Aoyagic  and  Yuji Miyahara*ac  

* Corresponding authors

a Center for NanoBio Integration, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
E-mail: amatsumoto@bmw.t.u-tokyo.ac.jp
Fax: +81 3 5841 1797
Tel: +81 3 5841 1797

b Department of Nanostructure and Advanced Materials, Kagoshima University, 1-21-40 Korimoto, Kagoshima 890-0065, Japan
E-mail: yamamoto@eng.kagoshima-u.ac.jp
Fax: +81 99 285 7794
Tel: +81 99 285 7794

c Biomaterials Center and International Center for Materials Nanoarchitectonics, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan
E-mail: MIYAHARA.Yuji@nims.go.jp
Fax: +81 29 860 4714
Tel: +81 29 860 4506

Abstract

Here described is a phenylboronic acid (PBA) based glucose-responsive hydrogel operating under physiological pH and temperature, a material potentially applicable to a totally synthetic smart insulin delivery system to treat diabetes.

Graphical abstract: A totally synthetic glucose responsive gel operating in physiological aqueous conditions

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Article information

DOI
https://doi.org/10.1039/B920319B
Article type
Communication
Submitted
29 Sep 2009
Accepted
03 Dec 2009
First published
07 Jan 2010

Chem. Commun., 2010,46, 2203-2205

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A totally synthetic glucose responsive gel operating in physiological aqueous conditions

A. Matsumoto, K. Yamamoto, R. Yoshida, K. Kataoka, T. Aoyagi and Y. Miyahara, Chem. Commun., 2010, 46, 2203 DOI: 10.1039/B920319B

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