Issue 27, 2011

Encoded peptide libraries and the discovery of new cell binding ligands

Abstract

Cells over-expressing integrins or CCR6 were incubated on a DNA microarray, pre-hybridized with a 10 000 member PNA-encoded peptide library allowing novel cell specific ligands for integrins and CCR6 to be identified.

Graphical abstract: Encoded peptide libraries and the discovery of new cell binding ligands

Supplementary files

Article information

Article type
Communication
Submitted
23 Mar 2011
Accepted
12 May 2011
First published
09 Jun 2011

Chem. Commun., 2011,47, 7638-7640

Encoded peptide libraries and the discovery of new cell binding ligands

N. Svensen, J. J. Díaz-Mochón and M. Bradley, Chem. Commun., 2011, 47, 7638 DOI: 10.1039/C1CC11668A

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