Immobilization of folic acid on Eu3+-doped nanoporous silica spheres

Motohiro Tagaya; Toshiyuki Ikoma; Tomohiko Yoshioka; Zhefeng Xu; Junzo Tanaka

doi:10.1039/C1CC12058A

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Immobilization of folic acid on Eu³⁺-doped nanoporous silica spheres†

Motohiro Tagaya,*^ab Toshiyuki Ikoma,^a Tomohiko Yoshioka,^a Zhefeng Xu^a and Junzo Tanaka^a

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* Corresponding authors

^a Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, O-okayama 2-12-1, Meguro-ku, Tokyo 152-8550, Japan
E-mail: tagaya.m.aa@m.titech.ac.jp
Fax: +81-3-5734-3369
Tel: +81-3-5734-3960

^b Research Fellow of the Japan Society for the Promotion of Science, Tokyo, Japan

Abstract

Folic acid (FA) was immobilized on Eu³⁺-doped nanoporous silica spheres (Eu:NPSs) through mediation of the 3-aminopropyltriethoxysilane adlayer. The ordered nanopores of Eu:NPS were preserved by the immobilization. The FA-immobilized Eu:NPSs showed the characteristic photoluminescence peak due to interactions between the FA molecules and Eu³⁺ ions, and highly dispersed stability in phosphate buffered saline.

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Article information

DOI: https://doi.org/10.1039/C1CC12058A
Article type: Communication
Submitted: 11 Apr 2011
Accepted: 08 Jun 2011
First published: 25 Jun 2011

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Chem. Commun., 2011,47, 8430-8432

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Immobilization of folic acid on Eu³⁺-doped nanoporous silica spheres

M. Tagaya, T. Ikoma, T. Yoshioka, Z. Xu and J. Tanaka, Chem. Commun., 2011, 47, 8430 DOI: 10.1039/C1CC12058A

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Chemical Communications