Issue 30, 2011
From the journal:

Chemical Communications

CdSe/ZnS quantum dot–Cytochrome cbioconjugates for selective intracellular O2˙− sensing†

Da-Wei Li,‡a   Li-Xia Qin,‡a   Yang Li,a   Raheleh Partovi Nia,b   Yi-Tao Long*a  and  Hong-Yuan Chenc  

* Corresponding authors

a Shanghai Key Laboratory of Functional Materials Chemistry & Department of Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, P.R. China
E-mail: ytlong@ecust.edu.cn
Fax: +86-21-64250032

b The University of Western Ontario, Canada

c Department of Chemistry, Nanjing University, Nanjing 210093, P.R. China

Abstract

We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O2˙−) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

Graphical abstract: CdSe/ZnS quantum dot–Cytochrome c bioconjugates for selective intracellular O2˙− sensing

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Article information

DOI
https://doi.org/10.1039/C1CC13160E
Article type
Communication
Submitted
29 May 2011
Accepted
20 Jun 2011
First published
28 Jun 2011

Chem. Commun., 2011,47, 8539-8541

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CdSe/ZnS quantum dot–Cytochrome c bioconjugates for selective intracellular O2˙− sensing

D. Li, L. Qin, Y. Li, R. P. Nia, Y. Long and H. Chen, Chem. Commun., 2011, 47, 8539 DOI: 10.1039/C1CC13160E

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