Issue 4, 2011
From the journal:

Organic & Biomolecular Chemistry

Total synthesis of cyanolide A†

Zhen Yang,a   Xingang Xie,a   Peng Jing,a   Gaoyuan Zhao,a   Jiyue Zheng,a   Changgui Zhaoa  and  Xuegong She*ab  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, People's Republic of China

b State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, People's Republic of China
E-mail: shexg@lzu.edu.cn
Fax: +86-931-8912582
Tel: +86-931-8912276

Abstract

The total synthesis of cyanolide A has been achieved in 14 steps from commercially available (S)-2-ethyloxirane, exploiting the palladium-catalyzed intramolecular alkoxycarbonylation as the key step to construct the tetrasubstituted cis-tetrahydropyran ring with high stereoselectivity.

Graphical abstract: Total synthesis of cyanolide A

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0OB00971G
Article type
Communication
Submitted
02 Nov 2010
Accepted
29 Nov 2010
First published
13 Dec 2010

Org. Biomol. Chem., 2011,9, 984-986

Permissions

Request permissions

Total synthesis of cyanolide A

Z. Yang, X. Xie, P. Jing, G. Zhao, J. Zheng, C. Zhao and X. She, Org. Biomol. Chem., 2011, 9, 984 DOI: 10.1039/C0OB00971G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements