Issue 44, 2012
From the journal:

Chemical Communications

Pharmaceutically active ionic liquids with solids handling, enhanced thermal stability, and fast release†‡

Katharina Bica,a   Héctor Rodríguez,b   Gabriela Gurau,c   O. Andreea Cojocaru,c   Anders Riisager,d   Rasmus Fehrmannd  and  Robin D. Rogers*c  

* Corresponding authors

a Institute of Applied Synthetic Chemistry, Vienna University of Technology, 1060 Vienna, Austria

b Department of Chemical Engineering, University of Santiago de Compostela, Santiago de Compostela, Spain

c Center for Green Manufacturing and Department of Chemistry, The University of Alabama, Tuscaloosa, USA
E-mail: rdrogers@as.ua.edu

d Department of Chemistry & Centre for Catalysis and Sustainable Chemistry (CSC), Technical University of Denmark, B207, DK-2800 Kgs. Lyngby, Denmark

Abstract

Pharmaceutically active compounds in ionic liquid form immobilized onto mesoporous silica are stable, easily handled solids, with fast and complete release from the carrier material when placed into an aqueous environment. Depending on specific ion-surface interactions, they may also exhibit improved thermal stability when compared to the non-adsorbed compounds.

Graphical abstract: Pharmaceutically active ionic liquids with solids handling, enhanced thermal stability, and fast release

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Article information

DOI
https://doi.org/10.1039/C2CC30959A
Article type
Communication
Submitted
09 Feb 2012
Accepted
27 Mar 2012
First published
28 Mar 2012

Chem. Commun., 2012,48, 5422-5424

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Pharmaceutically active ionic liquids with solids handling, enhanced thermal stability, and fast release

K. Bica, H. Rodríguez, G. Gurau, O. Andreea Cojocaru, A. Riisager, R. Fehrmann and R. D. Rogers, Chem. Commun., 2012, 48, 5422 DOI: 10.1039/C2CC30959A

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