Issue 67, 2012
From the journal:

Chemical Communications

Chemical speciation of nanoparticles surrounding metal-on-metal hips†

Angela E. Goode,a   James M. Perkins,a   Ann Sandison,b   Chithra Karunakaran,c   Huikai Cheng,d   David Wall,d   John A. Skinner,e   Alister J. Hart,f   Alexandra E. Porter,*a   David W. McComb*ag  and  Mary P. Ryan*a  

* Corresponding authors

a Department of Materials, Imperial College London, London, UK

b Department of Orthopaedics, Royal National Orthopaedic Hospital, UK

c Canadian Light Source, Saskatoon, Canada

d FEI Company, The Netherlands & USA

e Centre for Clinical Orthopaedics, University College London, London, UK

f Charing Cross Hospital, Imperial College London, London, UK

g Department of Materials Science & Engineering, The Ohio State University, USA

Abstract

Spectromicroscopy of tissue surrounding failed CoCr metal-on-metal hip replacements detected corroded nanoscale debris in periprosthetic tissue in two chemical states, with concomitant mitochondrial damage. The majority of debris contained Cr3+, with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed.

Graphical abstract: Chemical speciation of nanoparticles surrounding metal-on-metal hips

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Article information

DOI
https://doi.org/10.1039/C2CC33016D
Article type
Communication
Submitted
26 Apr 2012
Accepted
12 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 8335-8337

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Chemical speciation of nanoparticles surrounding metal-on-metal hips

A. E. Goode, J. M. Perkins, A. Sandison, C. Karunakaran, H. Cheng, D. Wall, J. A. Skinner, A. J. Hart, A. E. Porter, D. W. McComb and M. P. Ryan, Chem. Commun., 2012, 48, 8335 DOI: 10.1039/C2CC33016D

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