Issue 94, 2012

Conserved RNA motifs of EMCV IRES as potential building blocks to design RNA nanostructures

Abstract

The highly conserved secondary structural RNA motifs endowed by the IRES element of EMCV picornavirus provide an excellent platform to design RNA nanostructures for application in medicine. We have identified a 44mer RNA, hosting distinct 15mer and 11mer RNA stem loop motifs, as potential building blocks for the design of RNA nanostructures.

Graphical abstract: Conserved RNA motifs of EMCV IRES as potential building blocks to design RNA nanostructures

Supplementary files

Article information

Article type
Communication
Submitted
20 Aug 2012
Accepted
15 Oct 2012
First published
15 Oct 2012

Chem. Commun., 2012,48, 11573-11575

Conserved RNA motifs of EMCV IRES as potential building blocks to design RNA nanostructures

K. K. Chan and V. Ramesh, Chem. Commun., 2012, 48, 11573 DOI: 10.1039/C2CC36034A

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