Issue 92, 2012
From the journal:

Chemical Communications

A zwitterionic squaraine dye with a large Stokes shift for in vivo and site-selective protein sensing†

Yongqian Xu,a   Qin Liu,b   Xiaopeng Li,a   Chrys Wesdemiotisa  and  Yi Pang*a  

* Corresponding authors

a Department of Chemistry & Maurice Morton Institute of Polymer Science, The University of Akron, Akron, USA
E-mail: yp5@uakron.edu

b Department of Biology, The University of Akron, Akron, USA

Abstract

A novel squaraine dye (SQ) exhibits improved fluorescence response toward protein detection by incorporation of a zwitterionic structure. With the aid of a dansylamide (DNSA) substituent, the new probe (DNSA-SQ) exhibits remarkable selectivity in binding to site I (a specific substructure in protein).

Graphical abstract: A zwitterionic squaraine dye with a large Stokes shift for in vivo and site-selective protein sensing

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Article information

DOI
https://doi.org/10.1039/C2CC36285F
Article type
Communication
Submitted
29 Aug 2012
Accepted
04 Oct 2012
First published
08 Oct 2012

Chem. Commun., 2012,48, 11313-11315

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A zwitterionic squaraine dye with a large Stokes shift for in vivo and site-selective protein sensing

Y. Xu, Q. Liu, X. Li, C. Wesdemiotis and Y. Pang, Chem. Commun., 2012, 48, 11313 DOI: 10.1039/C2CC36285F

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