Issue 4, 2012
From the journal:

RSC Advances

An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions†‡

Ondřej Baszczyňski,a   Petr Jansa,a   Martin Dračínský,a   Martin Maxmilian Kaiser,a   Petr Špačeka  and  Zlatko Janeba*a  

* Corresponding authors

a Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Flemingovo nám. 2, Prague 6, Czech Republic
E-mail: janeba@uochb.cas.cz

Abstract

An oxa-Michael addition of various secondary and branched primary alcohols to diethyl vinylphosphonate was systematically studied and optimized. This efficient method precedes using of harsh reaction conditions (e.g. strong bases, high temperatures) and gains access to an important class of biologically active compounds in one step.

Graphical abstract: An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2RA00938B
Article type
Communication
Submitted
21 Oct 2011
Accepted
21 Nov 2011
First published
15 Dec 2011

RSC Adv., 2012,2, 1282-1284

Permissions

Request permissions

An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions

O. Baszczyňski, P. Jansa, M. Dračínský, M. M. Kaiser, P. Špaček and Z. Janeba, RSC Adv., 2012, 2, 1282 DOI: 10.1039/C2RA00938B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements