Issue 61, 2013
From the journal:

Chemical Communications

Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow†

Naresh K. Mani,abc   Sergii Rudiukabc  and  Damien Baigl*abc  

* Corresponding authors

a Department of Chemistry, Ecole Normale Supérieure, 75005 Paris, France
E-mail: damien.baigl@ens.fr
Web: http://www.baigllab.com/
Tel: +33 1 4432 2405

b Université Pierre et Marie Curie – Paris 6, 75005 Paris, France

c UMR 8640, CNRS, France

Abstract

A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.

Graphical abstract: Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC44016H
Article type
Communication
Submitted
28 May 2013
Accepted
10 Jun 2013
First published
11 Jun 2013

Chem. Commun., 2013,49, 6858-6860

Permissions

Request permissions

Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

N. K. Mani, S. Rudiuk and D. Baigl, Chem. Commun., 2013, 49, 6858 DOI: 10.1039/C3CC44016H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements