Issue 2, 2013
From the journal:

Lab on a Chip

Spatially resolved electrochemical sensing of chemical gradients†

Meghan M. Mensack,a   John B. Wydallis,a   N. Scott Lynn, Jr.,b   David S. Dandyc  and  Charles S. Henry*ac  

* Corresponding authors

a Department of Chemistry, Colorado State University, 1872 Campus Delivery, Fort Collins, Colorado, USA
E-mail: chuck.henry@colostate.edu
Fax: +1 970-491-1801
Tel: +1 970-491-2852

b Institute of Photonics and Electronics, Academy of Sciences of the Czech Republic, Prague, Czech Republic

c Department of Chemical and Biological engineering, Colorado State University, 1370 Campus Delivery, Fort Collins, Colorado, USA

Abstract

Chemical gradients drive a diverse set of biological processes ranging from nerve transduction to ovulation. At present, the most common method for quantifying chemical gradients is microscopy. Here, a new concept for probing spatial and temporal chemical gradients is reported that uses a multi-layer microfluidic device to measure analyte concentration as a function of lateral position in a microfluidic channel using electrochemistry in a format that is readily adaptable to multi-analyte sensing.

Graphical abstract: Spatially resolved electrochemical sensing of chemical gradients

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Article information

DOI
https://doi.org/10.1039/C2LC41054K
Article type
Communication
Submitted
18 Sep 2012
Accepted
08 Nov 2012
First published
09 Nov 2012

Lab Chip, 2013,13, 208-211

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Spatially resolved electrochemical sensing of chemical gradients

M. M. Mensack, J. B. Wydallis, N. S. Lynn, D. S. Dandy and C. S. Henry, Lab Chip, 2013, 13, 208 DOI: 10.1039/C2LC41054K

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