Issue 6, 2013
From the journal:

Nanoscale

Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering†

Angelo Accardo,a   Luca Tirinato,a   Davide Altamura,b   Teresa Sibillano,b   Cinzia Giannini,b   Christian Riekelc  and  Enzo Di Fabrizio*de  

* Corresponding authors

a Istituto Italiano di Tecnologia (IIT), Nanostructures Department, via Morego 30, 16163 Genova, Italy

b Istituto di Cristallografia – Consiglio Nazionale delle Ricerche (IC-CNR), Via Amendola 122/O, 70126 Bari, Italy

c European Synchrotron Radiation Facility, B.P.220, F-38043 Grenoble Cedex, France

d KAUST (King Abdullah University of Science and Technology) PSE and BESE divisions, Jeddah, Saudi Arabia

e BIONEM lab University of Magna Graecia, Campus Salvatore Venuta, Viale Europa 88100, Germaneto-Catanzaro, Italy
E-mail: enzo.difabrizio@iit.it

Abstract

Drops of exosome dispersions from healthy epithelial colon cell line and colorectal cancer cells were dried on a superhydrophobic PMMA substrate. The residues were studied by small- and wide-angle X-ray scattering using both a synchrotron radiation micrometric beam and a high-flux table-top X-ray source. Structural differences between healthy and cancerous cells were detected in the lamellar lattices of the exosome macro-aggregates.

Graphical abstract: Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering

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Article information

DOI
https://doi.org/10.1039/C3NR34032E
Article type
Communication
Submitted
10 Dec 2012
Accepted
02 Feb 2013
First published
06 Feb 2013

Nanoscale, 2013,5, 2295-2299

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Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering

A. Accardo, L. Tirinato, D. Altamura, T. Sibillano, C. Giannini, C. Riekel and E. Di Fabrizio, Nanoscale, 2013, 5, 2295 DOI: 10.1039/C3NR34032E

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