Issue 22, 2014

Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins

Abstract

Monodisperse sphere-on-sphere (SOS) silica particles are produced in a one-pot reaction, removing the need for time-consuming preparation and classification steps. Analysis of peptides and proteins using HPLC displays faster separation at lower operating pressure than commercially available fused core materials.

Graphical abstract: Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins

Supplementary files

Article information

Article type
Communication
Submitted
04 Aug 2014
Accepted
12 Sep 2014
First published
12 Sep 2014

Analyst, 2014,139, 5674-5677

Author version available

Monodisperse sphere-on-sphere silica particles for fast HPLC separation of peptides and proteins

R. Hayes, P. Myers, T. Edge and H. Zhang, Analyst, 2014, 139, 5674 DOI: 10.1039/C4AN01428F

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