Issue 14, 2014
From the journal:

Chemical Communications

Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: cellular characterization and mitochondria-specific localization†

Zhengqing Guo,a   Wah-Leung Tonga  and  Michael C. W. Chan*a  

* Corresponding authors

a Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
E-mail: mcwchan@cityu.edu.hk

Abstract

A readily tunable series of non-planar oligo(ethylene glycol)-substituted phosphorescent Pt(II) complexes has been investigated as live cell imaging agents; suitable structural modifications can give good cellular uptake, traceable mitochondria-specific localization and potent cytotoxic characteristics towards HeLa cells.

Graphical abstract: Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(ii) complexes: cellular characterization and mitochondria-specific localization

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Article information

DOI
https://doi.org/10.1039/C3CC47150K
Article type
Communication
Submitted
18 Sep 2013
Accepted
04 Dec 2013
First published
04 Dec 2013

Chem. Commun., 2014,50, 1711-1714

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Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(II) complexes: cellular characterization and mitochondria-specific localization

Z. Guo, W. Tong and M. C. W. Chan, Chem. Commun., 2014, 50, 1711 DOI: 10.1039/C3CC47150K

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