Issue 63, 2014
From the journal:

Chemical Communications

A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening†

Yongqian Xu,*a   Benhao Li,b   Liangliang Xiao,a   Jia Ouyang,d   Shiguo Sun*a  and  Yi Pangc  

* Corresponding authors

a College of Science, Northwest A&F University, Yangling, P. R. China
E-mail: xuyq@nwsuaf.edu.cn, sunsg@nwsuaf.edu.cn

b School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, P. R. China

c Department of Chemistry & Maurice Morton Institute of Polymer Science, The University of Akron, Akron, OH, USA

d School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an, P. R. China

Abstract

A dual-channel including a colorimetric and fluorescent probe based on the aggregation-caused quenching (ACQ) and enzymolysis approach has been presented to screen acid phosphatase (ACP) and its inhibitor. Moreover, the ACP activity was determined by real time assay.

Graphical abstract: A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

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Article information

DOI
https://doi.org/10.1039/C3CC49254K
Article type
Communication
Submitted
05 Dec 2013
Accepted
09 Jun 2014
First published
09 Jun 2014

Chem. Commun., 2014,50, 8677-8680

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A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

Y. Xu, B. Li, L. Xiao, J. Ouyang, S. Sun and Y. Pang, Chem. Commun., 2014, 50, 8677 DOI: 10.1039/C3CC49254K

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