Issue 66, 2014
From the journal:

Chemical Communications

Directed self-assembly of polypeptide-engineered physical microgels for building porous cell-laden hydrogels†

Ming-Hao Yao,a   Jie Yang,a   Ji-Tao Song,a   Dong-Hui Zhao,a   Ming-Shuo Du,a   Yuan-Di Zhao*a  and  Bo Liu*a  

* Corresponding authors

a Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics – Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, Hubei, P. R. China
E-mail: zydi@mail.hust.edu.cn, lbyang@mail.hust.edu.cn
Fax: +86-27-8779-2202

Abstract

A novel approach to build porous cell-laden hydrogels through the self-assembly of coiled-coil polypeptides on the surface of physical microgels was developed. Both the extracellular microenvironments of pores and physical microgels within assembled constructs could be tailored simultaneously by tuning the polypeptide and morphological features of microgels.

Graphical abstract: Directed self-assembly of polypeptide-engineered physical microgels for building porous cell-laden hydrogels

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Article information

DOI
https://doi.org/10.1039/C4CC04018J
Article type
Communication
Submitted
26 May 2014
Accepted
01 Jul 2014
First published
01 Jul 2014

Chem. Commun., 2014,50, 9405-9408

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Directed self-assembly of polypeptide-engineered physical microgels for building porous cell-laden hydrogels

M. Yao, J. Yang, J. Song, D. Zhao, M. Du, Y. Zhao and B. Liu, Chem. Commun., 2014, 50, 9405 DOI: 10.1039/C4CC04018J

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