Issue 26, 2014

A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

Abstract

Based on a novel coumarin-quinolinium platform, probe 2 was rationally designed and synthesized as a novel ratiometric fluorescent sensor for sulfite anions. The probe exhibited a wide dynamic concentration range for sulfite anions in a PBS buffer (containing 1 mg mL−1 BSA). More importantly, the probe was suitable for ratiometric fluorescence imaging in living cells with high sensitivity, favorable selectivity, and minimal cytotoxicity.

Graphical abstract: A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

Supplementary files

Article information

Article type
Paper
Submitted
18 Jan 2014
Accepted
02 May 2014
First published
02 May 2014

Org. Biomol. Chem., 2014,12, 4637-4643

A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

L. Tan, W. Lin, S. Zhu, L. Yuan and K. Zheng, Org. Biomol. Chem., 2014, 12, 4637 DOI: 10.1039/C4OB00132J

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