A novel platform for detection of protooncogene based on Au nanocluster enhanced fluorescence

Kang Mao; Yizhen Liu; Huaming Xiao; Yinran Chen; Zitong Wu; Xiaodong Zhou; Aiguo Shen; Jiming Hu

doi:10.1039/C4AY02117G

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A novel platform for detection of protooncogene based on Au nanocluster enhanced fluorescence†

Kang Mao,^a Yizhen Liu,^ab Huaming Xiao,^a Yinran Chen,^a Zitong Wu,^a Xiaodong Zhou,*^a Aiguo Shen^a and Jiming Hu^a

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* Corresponding authors

^a Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, China
E-mail: zhouxd@whu.edu.cn
Tel: +86 027 68752439 8116

^b College of Chemistry and Chemical Engineering, Shenzhen University, Shenzhen 518060, Guangdong, China

Abstract

For the first time, gold nanoclusters were found to exhibit high fluorescence enhancement ability based on the metal-enhanced fluorescence (MEF) effect, which can effectively enhance the fluorescence of fluorescein isothiocyanate (FITC). By means of this phenomenon, Au nanoclusters have been successfully used in the construction of a fluorescence-enhanced sensing platform for the detection of protooncogene.

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Article information

DOI: https://doi.org/10.1039/C4AY02117G
Article type: Communication
Submitted: 10 Sep 2014
Accepted: 04 Nov 2014
First published: 05 Nov 2014

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Anal. Methods, 2015,7, 40-44

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A novel platform for detection of protooncogene based on Au nanocluster enhanced fluorescence

K. Mao, Y. Liu, H. Xiao, Y. Chen, Z. Wu, X. Zhou, A. Shen and J. Hu, Anal. Methods, 2015, 7, 40 DOI: 10.1039/C4AY02117G

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Analytical Methods

A novel platform for detection of protooncogene based on Au nanocluster enhanced fluorescence†

Abstract

Supplementary files

Article information

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A novel platform for detection of protooncogene based on Au nanocluster enhanced fluorescence

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