A sensitive hydrogen peroxide sensor based on a three-dimensional N-doped carbon nanotube-hemin modified electrode

Abstract

In this work, a large-scale synthesis of a three-dimensional (3D) nitrogen-doped carbon nanotube (NCNT) film was achieved via electrospinning assisted by a chemical vapor deposition procedure. The resulting nanostructure with dense and uniform NCNTs was tightly bonded onto the electrospun carbon nanofiber matrix. Owing to the favorable 3D network structure and high nitrogen doping, the 3D NCNTs are a wonderful platform to immobilize hemin for biosensing. By directly dropping the flexible film onto the electrode surface without additional oxidant treatment, a H₂O₂ biosensor can be simply constructed. The novel biomimetic H₂O₂ biosensor has a low detection limit (0.03 µM S/N = 3) and a wide linear range (0.08–137.2 µM). The excellent synergic effect enables an enhanced electrochemical performance of the modified electrode with good biocompatibility and fast redox properties. In addition, the biosensor exhibited high reproducibility, good storage stability, and satisfactory anti-interference ability. The facile preparation method and attractive analytical performances make this robust electrode material promising for the development of effective electrochemical sensors.