A cucurbit[5]uril analogue from dimethylpropanediurea–formaldehyde condensation

Abstract

A new host Me₁₀TD[5] was prepared for the first time from propanediurea–formaldehyde condensation. Me₁₀TD[5] is soluble in both water and common organic solvents, and binds protonated amines in a 1 : 2 stoichiometry in H₂O with the K₁ and K₂ values on the order of 10³ M⁻¹. The self-assembly of Me₁₀TD[5] with 1,4-xylylene diamine dihydrochloride results in the formation of a linear supramolecular polymer.