Issue 3, 2015
From the journal:

Lab on a Chip

Microencapsulation of indocyanine green for potential applications in image-guided drug delivery†

Zhiqiang Zhu,ac   Ting Si*bc  and  Ronald X. Xu*ac  

* Corresponding authors

a Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, Anhui 230026, PR China

b Department of Modern Mechanics, University of Science and Technology of China, Hefei, Anhui 230026, PR China
E-mail: tsi@ustc.edu.cn

c Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA
E-mail: xu.ronald@hotmail.com
Fax: +1 614 292 7301
Tel: +1 614 688 3635

Abstract

We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging.

Graphical abstract: Microencapsulation of indocyanine green for potential applications in image-guided drug delivery

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Article information

DOI
https://doi.org/10.1039/C4LC01032A
Article type
Communication
Submitted
03 Sep 2014
Accepted
20 Nov 2014
First published
21 Nov 2014

Lab Chip, 2015,15, 646-649

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Microencapsulation of indocyanine green for potential applications in image-guided drug delivery

Z. Zhu, T. Si and R. X. Xu, Lab Chip, 2015, 15, 646 DOI: 10.1039/C4LC01032A

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