We synthesised a novel membrane-insertable amphiphilic DNA. The amphiphilic DNA had a nine-nucleotide hydrophobic region at one end consisting of octyl phosphotriester linkages. The amphiphilic DNA bound to the lipid membrane by inserting the hydrophobic region; this process was facilitated by the presence of the complementary DNA strand.
C. Dohno, K. Matsuzaki, H. Yamaguchi, T. Shibata and K. Nakatani, Org. Biomol. Chem., 2015, 13, 10117 DOI: 10.1039/C5OB01761K
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