Issue 52, 2015
From the journal:

RSC Advances

An efficient aqueous phase synthesis of benzimidazoles/benzothiazoles in the presence of β-cyclodextrin†

Ramesh Katla,a   Rakhi Chowrasia,b   Padma Sunitha Manjarib  and  Nelson Luís C. Domingues*a  

* Corresponding authors

a Organic Catalysis and Biocatalysis Laboratory OCBL/FACET, Federal University of Grande Dourados—UFGD, Dourados/Itahúm rod. km 12 s/n, Zip Code 79804-970, Dourados, MS, Brazil
E-mail: nelsondomingues@ufgd.edu.br

b Department of Chemistry, Osmania University, Hyderabad, India

Abstract

Benzimidazoles/benzothiazoles were synthesized in water under neutral conditions by the reaction of aromatic aldehydes, o-phenylenediamine/2-amino thiophenol mediated by β-cyclodextrin in high yields. β-Cyclodextrin can be recovered and reused without significant loss of activity.

Graphical abstract: An efficient aqueous phase synthesis of benzimidazoles/benzothiazoles in the presence of β-cyclodextrin

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Article information

DOI
https://doi.org/10.1039/C4RA16222F
Article type
Paper
Submitted
11 Dec 2014
Accepted
23 Apr 2015
First published
24 Apr 2015

RSC Adv., 2015,5, 41716-41720

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An efficient aqueous phase synthesis of benzimidazoles/benzothiazoles in the presence of β-cyclodextrin

R. Katla, R. Chowrasia, P. S. Manjari and N. L. C. Domingues, RSC Adv., 2015, 5, 41716 DOI: 10.1039/C4RA16222F

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