Issue 13, 2016
From the journal:

Chemical Communications

Light-controlled reactive oxygen species (ROS)-producible polymeric micelles with simultaneous drug-release triggering and endo/lysosomal escape†

Kihong Kim,‡a   Chung-Sung Lee‡a  and  Kun Na*a  

* Corresponding authors

a Department of Biotechnology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi-do, Republic of Korea
E-mail: kna6997@catholic.ac.kr

Abstract

A doxorubicin (DOX)-loaded and light-induced ROS-producing polymeric micelle (D-LRPM), in which light triggers simultaneous DOX-release and endo/lysosomal escape, produces a powerful, spatiotemporally controllable, therapeutic efficacy for tumor treatment.

Graphical abstract: Light-controlled reactive oxygen species (ROS)-producible polymeric micelles with simultaneous drug-release triggering and endo/lysosomal escape

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Article information

DOI
https://doi.org/10.1039/C5CC09239F
Article type
Communication
Submitted
10 Nov 2015
Accepted
08 Jan 2016
First published
08 Jan 2016

Chem. Commun., 2016,52, 2839-2842

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Light-controlled reactive oxygen species (ROS)-producible polymeric micelles with simultaneous drug-release triggering and endo/lysosomal escape

K. Kim, C. Lee and K. Na, Chem. Commun., 2016, 52, 2839 DOI: 10.1039/C5CC09239F

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